Simultaneous POMC Gene Transfer to Hypothalamus and Brainstem Increases Physical Activity, Lipolysis and Reduces Adult-Onset Obesity

Pro-opiomelanocortin (POMC) neurons are identified in two brain sites, the arcuate nucleus (ARC) of the hypothalamus and nucleus of the solitary tract (NTS) in brainstem. Earlier pharmacological and POMC gene transfer studies demonstrate melanocortin activation in either site alone improves insulin...

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Detalhes bibliográficos
Main Authors: Zhang, Yi, Rodrigues, Enda, Li, Gang, Gao, Yongxin, King, Michael, Carter, Christy S., Tumer, Nihal, Cheng, Kit-Yan, Scarpace, Philip J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079048/
https://ncbi.nlm.nih.gov/pubmed/21366729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2011.07633.x
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