The Act of Voluntary Wheel Running Reverses Dietary Hyperphagia and Increases Leptin Signaling in Ventral Tegmental Area of Aged Obese Rats

To test the hypothesis that exercise increases central leptin signaling, and thus reduces dietary weight gain in an aged obese model, we assessed the effects of voluntary wheel running (WR) in 23-month-old F344×BN rats fed a 60% high-fat (HF) diet for 3 months. After 2 months on the HF diet, half of...

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Bibliografiske detaljer
Main Authors: Shapiro, Alexandra, Cheng, Kit-Yan, Gao, Yongxin, Seo, Dong-oh, Anton, Steve, Carter, Christy S., Zhang, Yi, Tumer, Nihal, Scarpace, Philip J.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2011
Fag:
Experimental Section / Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130980/
https://ncbi.nlm.nih.gov/pubmed/20881371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321343
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