The Act of Voluntary Wheel Running Reverses Dietary Hyperphagia and Increases Leptin Signaling in Ventral Tegmental Area of Aged Obese Rats

To test the hypothesis that exercise increases central leptin signaling, and thus reduces dietary weight gain in an aged obese model, we assessed the effects of voluntary wheel running (WR) in 23-month-old F344×BN rats fed a 60% high-fat (HF) diet for 3 months. After 2 months on the HF diet, half of...

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Detalhes bibliográficos
Main Authors: Shapiro, Alexandra, Cheng, Kit-Yan, Gao, Yongxin, Seo, Dong-oh, Anton, Steve, Carter, Christy S., Zhang, Yi, Tumer, Nihal, Scarpace, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Experimental Section / Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130980/
https://ncbi.nlm.nih.gov/pubmed/20881371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321343
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