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RNA helical imperfections regulate activation of the protein kinase PKR: Effects of bulge position, size, and geometry
The protein kinase, PKR, is activated by long stretches of double-stranded (ds) RNA. Viruses often make long dsRNA elements with imperfections that still activate PKR. However, due to the complexity of the RNA structure, prediction of whether a given RNA is an activator of PKR is difficult. Herein,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078744/ https://ncbi.nlm.nih.gov/pubmed/21460237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2636911 |
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