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Straightening of bulged RNA by the double-stranded RNA-binding domain from the protein kinase PKR

The human interferon-induced protein kinase, PKR, is an antiviral agent that is activated by long stretches of double-stranded (ds)RNA. PKR has an N-terminal dsRNA-binding domain that contains two tandem copies of the dsRNA-binding motif and interacts with dsRNA in a nonsequence-specific fashion. Su...

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Detalhes bibliográficos
Main Authors: Zheng, Xiaofeng, Bevilacqua, Philip C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18888/
https://ncbi.nlm.nih.gov/pubmed/11114159
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