Straightening of bulged RNA by the double-stranded RNA-binding domain from the protein kinase PKR
The human interferon-induced protein kinase, PKR, is an antiviral agent that is activated by long stretches of double-stranded (ds)RNA. PKR has an N-terminal dsRNA-binding domain that contains two tandem copies of the dsRNA-binding motif and interacts with dsRNA in a nonsequence-specific fashion. Su...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18888/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11114159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.011355798 |
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