Novel Protective Properties of IGFBP-3 Result in Enhanced Pericyte Ensheathment, Reduced Microglial Activation, Increased Microglial Apoptosis, and Neuronal Protection after Ischemic Retinal Injury

This study was conducted to determine the perivascular cell responses to increased endothelial cell expression of insulin-like growth factor binding protein-3 (IGFBP-3) in mouse retina. The contribution of bone marrow cells in the IGFBP-3–mediated response was examined using green fluorescent protei...

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Main Authors: Kielczewski, Jennifer L., Hu, Ping, Shaw, Lynn C., Li Calzi, Sergio, Mames, Robert N., Gardiner, Tom A., McFarland, Evan, Chan-Ling, Tailoi, Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078432/
https://ncbi.nlm.nih.gov/pubmed/21435441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.031
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