Novel Protective Properties of IGFBP-3 Result in Enhanced Pericyte Ensheathment, Reduced Microglial Activation, Increased Microglial Apoptosis, and Neuronal Protection after Ischemic Retinal Injury

This study was conducted to determine the perivascular cell responses to increased endothelial cell expression of insulin-like growth factor binding protein-3 (IGFBP-3) in mouse retina. The contribution of bone marrow cells in the IGFBP-3–mediated response was examined using green fluorescent protei...

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Bibliografske podrobnosti
Main Authors: Kielczewski, Jennifer L., Hu, Ping, Shaw, Lynn C., Li Calzi, Sergio, Mames, Robert N., Gardiner, Tom A., McFarland, Evan, Chan-Ling, Tailoi, Grant, Maria B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078432/
https://ncbi.nlm.nih.gov/pubmed/21435441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.031
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