Novel Protective Properties of IGFBP-3 Result in Enhanced Pericyte Ensheathment, Reduced Microglial Activation, Increased Microglial Apoptosis, and Neuronal Protection after Ischemic Retinal Injury

This study was conducted to determine the perivascular cell responses to increased endothelial cell expression of insulin-like growth factor binding protein-3 (IGFBP-3) in mouse retina. The contribution of bone marrow cells in the IGFBP-3–mediated response was examined using green fluorescent protei...

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Hlavní autoři: Kielczewski, Jennifer L., Hu, Ping, Shaw, Lynn C., Li Calzi, Sergio, Mames, Robert N., Gardiner, Tom A., McFarland, Evan, Chan-Ling, Tailoi, Grant, Maria B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2011
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078432/
https://ncbi.nlm.nih.gov/pubmed/21435441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.031
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