Free Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) Reduces Retinal Vascular Permeability in Association with a Reduction of Acid Sphingomyelinase (ASMase)

PURPOSE. To examine the effect of free insulin-like growth factor (IGF) binding protein-3 (IGFBP-3), independent of the effect of insulin-like growth factors, in modulating retinal vascular permeability. METHODS. We assessed the ability of a form of IGFBP-3 that does not bind IGF-1 (IGFBP-3NB), to r...

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Detalhes bibliográficos
Main Authors: Kielczewski, Jennifer L., Calzi, Sergio Li, Shaw, Lynn C., Cai, Jun, Qi, Xiaoping, Ruan, Qing, Wu, Lin, Liu, Li, Hu, Ping, Chan-Ling, Tailoi, Mames, Robert N., Firth, Sue, Baxter, Robert C., Turowski, Patric, Busik, Julia V., Boulton, Michael E., Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208060/
https://ncbi.nlm.nih.gov/pubmed/21931131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8167
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