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Unsuspected pathway of the allosteric transition in hemoglobin

Large conformational transitions play an essential role in the function of many proteins, but experiments do not provide the atomic details of the path followed in going from one end structure to the other. For the hemoglobin tetramer, the transition path between the unliganded (T) and tetraoxygenat...

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Bibliografiska uppgifter
Huvudupphovsmän: Fischer, Stefan, Olsen, Kenneth W., Nam, Kwangho, Karplus, Martin
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078355/
https://ncbi.nlm.nih.gov/pubmed/21415366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011995108
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