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Unsuspected pathway of the allosteric transition in hemoglobin

Large conformational transitions play an essential role in the function of many proteins, but experiments do not provide the atomic details of the path followed in going from one end structure to the other. For the hemoglobin tetramer, the transition path between the unliganded (T) and tetraoxygenat...

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Autori principali: Fischer, Stefan, Olsen, Kenneth W., Nam, Kwangho, Karplus, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078355/
https://ncbi.nlm.nih.gov/pubmed/21415366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011995108
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