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Apoptosis is the essential tumor suppression function of p53 during mouse carcinoma progression

The high frequency of p53 mutation in human cancers indicates the important role of p53 in suppressing tumorigenesis. It is well established that the p53 regulates multiple, distinct, cellular functions such as cell cycle arrest and apoptosis. Despite intensive studies, little is known about which f...

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Detalhes bibliográficos
Main Authors: Lu, Xiangdong, Yang, Chunyu, Yin, Chaoying, Van Dyke, Terry, Simin, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078190/
https://ncbi.nlm.nih.gov/pubmed/21385880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0277
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