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p19(ARF) Is Dispensable for Oncogenic Stress-Induced p53-Mediated Apoptosis and Tumor Suppression In Vivo

Recent studies have shown the p19(ARF) tumor suppressor to be involved in the response to oncogenic stress by regulating the activity of p53. This response is mediated by antagonizing the function of Mdm2, a negative regulator of p53, indicating a pathway for tumor suppression that involves numerous...

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書誌詳細
主要な著者: Tolbert, Dawn, Lu, Xiangdong, Yin, Chaoying, Tantama, Mathew, Van Dyke, Terry
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC134227/
https://ncbi.nlm.nih.gov/pubmed/11739748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.370-377.2002
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