p19(ARF) Is Dispensable for Oncogenic Stress-Induced p53-Mediated Apoptosis and Tumor Suppression In Vivo

Recent studies have shown the p19(ARF) tumor suppressor to be involved in the response to oncogenic stress by regulating the activity of p53. This response is mediated by antagonizing the function of Mdm2, a negative regulator of p53, indicating a pathway for tumor suppression that involves numerous...

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Hlavní autoři: Tolbert, Dawn, Lu, Xiangdong, Yin, Chaoying, Tantama, Mathew, Van Dyke, Terry
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC134227/
https://ncbi.nlm.nih.gov/pubmed/11739748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.370-377.2002
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