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p19(ARF) Is Dispensable for Oncogenic Stress-Induced p53-Mediated Apoptosis and Tumor Suppression In Vivo

Recent studies have shown the p19(ARF) tumor suppressor to be involved in the response to oncogenic stress by regulating the activity of p53. This response is mediated by antagonizing the function of Mdm2, a negative regulator of p53, indicating a pathway for tumor suppression that involves numerous...

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Udgivet i:Mol Cell Biol
Principais autores: Tolbert, Dawn, Lu, Xiangdong, Yin, Chaoying, Tantama, Mathew, Van Dyke, Terry
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134227/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739748/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.1.370-377.2002
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