Nalaganje...
Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma
Chromosome translocations involving T cell receptor (TCR) loci have been found in tumors from Ataxia telangiectasia (AT) patients and in mouse Atm(−/−) thymoma, suggesting the involvement of V(D)J recombination in these malignancies. By introducing a RAG-1 deficiency into Atm(−/−) mice in the presen...
Shranjeno v:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
1999
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316723/ https://ncbi.nlm.nih.gov/pubmed/10346813 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|