Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation

Inflammation plays a role in the progression to cancer and it is linked to the presence of senescent cells. Ulcerative colitis (UC) is a chronic inflammatory disease that predisposes to colorectal cancer. Tumorigenesis in this setting is associated with telomere shortening that can be observed in th...

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Bibliografiska uppgifter
Huvudupphovsmän: Risques, Rosa Ana, Lai, Lisa A., Himmetoglu, Cigdem, Ebaee, Anoosheh, Li, Lin, Feng, Ziding, Bronner, Mary P., Al-Lahham, Bassel, Kowdley, Kris V., Lindor, Keith D., Rabinovitch, Peter S., Brentnall, Teresa A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077943/
https://ncbi.nlm.nih.gov/pubmed/21363920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1966
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