Ulcerative colitis is a disease of accelerated colon aging: evidence from telomere attrition and DNA damage

BACKGROUND & AIMS: Telomere shortening is implicated in cancer and aging, and might link these two biological events. We explored this hypothesis in ulcerative colitis, a chronic inflammatory disease that predisposes to colorectal cancer and where shorter telomeres have been associated with chro...

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Detalhes bibliográficos
Main Authors: Risques, Rosa Ana, Lai, Lisa A., Brentnall, Teresa A., Li, Lin, Feng, Ziding, Gallaher, Jasmine, Mandelson, Margaret T., Potter, John D., Bronner, Mary P., Rabinovitch, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574910/
https://ncbi.nlm.nih.gov/pubmed/18519043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.04.008
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