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Molecular biology and pathology of prion strains in sporadic human prion diseases

Prion diseases are believed to propagate by the mechanism involving self-perpetuating conformational conversion of the normal form of the prion protein, PrP(C), to the misfolded, pathogenic state, PrP(Sc). One of the most intriguing aspects of these disorders is the phenomenon of prion strains. It i...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Gambetti, Pierluigi, Cali, Ignazio, Notari, Silvio, Kong, Qingzhong, Zou, Wen-Quan, Surewicz, Witold K.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077936/
https://ncbi.nlm.nih.gov/pubmed/21058033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0761-3
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