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Molecular biology and pathology of prion strains in sporadic human prion diseases
Prion diseases are believed to propagate by the mechanism involving self-perpetuating conformational conversion of the normal form of the prion protein, PrP(C), to the misfolded, pathogenic state, PrP(Sc). One of the most intriguing aspects of these disorders is the phenomenon of prion strains. It i...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077936/ https://ncbi.nlm.nih.gov/pubmed/21058033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0761-3 |
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