Nephrocystin-4 Regulates Pyk2-induced Tyrosine Phosphorylation of Nephrocystin-1 to Control Targeting to Monocilia

Nephronophthisis is the most common genetic cause of end-stage renal failure during childhood and adolescence. Genetic studies have identified disease-causing mutations in at least 11 different genes (NPHP1–11), but the function of the corresponding nephrocystin proteins remains poorly understood. T...

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Главные авторы: Liebau, Max C., Höpker, Katja, Müller, Roman U., Schmedding, Ingolf, Zank, Sibylle, Schairer, Benjamin, Fabretti, Francesca, Höhne, Martin, Bartram, Malte P., Dafinger, Claudia, Hackl, Matthias, Burst, Volker, Habbig, Sandra, Zentgraf, Hanswalter, Blaukat, Andree, Walz, Gerd, Benzing, Thomas, Schermer, Bernhard
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2011
Предметы:
Molecular Bases of Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077625/
https://ncbi.nlm.nih.gov/pubmed/21357692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165464
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