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CaBP1 Regulates Voltage-dependent Inactivation and Activation of Ca(V)1.2 (L-type) Calcium Channels

CaBP1 is a Ca(2+)-binding protein that regulates the gating of voltage-gated (Ca(V)) Ca(2+) channels. In the Ca(V)1.2 channel α(1)-subunit (α(1C)), CaBP1 interacts with cytosolic N- and C-terminal domains and blunts Ca(2+)-dependent inactivation. To clarify the role of the α(1C) N-terminal domain in...

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Detalhes bibliográficos
Main Authors: Oz, Shimrit, Tsemakhovich, Vladimir, Christel, Carl J., Lee, Amy, Dascal, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077595/
https://ncbi.nlm.nih.gov/pubmed/21383011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198424
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