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Structural basis for the differential effects of CaBP1 and calmodulin on Ca(V)1.2 calcium-dependent inactivation

Calcium-binding protein 1 (CaBP1), a calmodulin (CaM) homolog, endows certain voltage-gated calcium channels (Ca(V)s) with unusual properties. CaBP1 inhibits Ca(V)1.2 calcium-dependent inactivation (CDI) and introduces calcium-dependent facilitation (CDF). Here, we show that the ability of CaBP1 to...

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Detalhes bibliográficos
Main Authors: Findeisen, Felix, Minor, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033571/
https://ncbi.nlm.nih.gov/pubmed/21134641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.09.012
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