Nature of the Amyloid-β Monomer and the Monomer-Oligomer Equilibrium

The monomer to oligomer transition initiates the aggregation and pathogenic transformation of Alzheimer amyloid-β (Aβ) peptide. However, the monomeric state of this aggregation-prone peptide has remained beyond the reach of most experimental techniques, and a quantitative understanding of this trans...

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Main Authors: Nag, Suman, Sarkar, Bidyut, Bandyopadhyay, Arkarup, Sahoo, Bankanidhi, Sreenivasan, Varun K. A., Kombrabail, Mamata, Muralidharan, Chandrakesan, Maiti, Sudipta
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Molecular Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077583/
https://ncbi.nlm.nih.gov/pubmed/21349839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.199885
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