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Decreased Expression and Androgen Regulation of the Tumor Suppressor Gene INPP4B in Prostate Cancer
Patients with metastatic prostate cancer who undergo androgen ablation therapy invariably relapse and develop incurable castration-resistant disease. Activation of the pro-survival Akt pathway accompanies androgen ablation. We discovered that androgen receptor (AR) induces expression of the tumor su...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077543/ https://ncbi.nlm.nih.gov/pubmed/21224358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2314 |
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