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Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities

The tumor suppressor INPP4B is an important regulator of phosphatidyl-inositol signaling in the cell. Reduced INPP4B expression is associated with poor outcomes for breast, prostate, and ovarian cancer patients. INPP4B contains a CX(5)R catalytic motif characteristic of dual-specificity phosphatases...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Lopez, Sandra M., Hodgson, Myles C., Packianathan, Charles, Bingol-Ozakpinar, Ozlem, Uras, Fikriye, Rosen, Barry P., Agoulnik, Irina U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578723/
https://ncbi.nlm.nih.gov/pubmed/24070612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.09.077
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