Decreased Expression and Androgen Regulation of the Tumor Suppressor Gene INPP4B in Prostate Cancer

Patients with metastatic prostate cancer who undergo androgen ablation therapy invariably relapse and develop incurable castration-resistant disease. Activation of the pro-survival Akt pathway accompanies androgen ablation. We discovered that androgen receptor (AR) induces expression of the tumor su...

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Bibliographic Details
Main Authors: Hodgson, Myles C., Shao, Long-jiang, Frolov, Anna, Li, Rile, Peterson, Leif E., Ayala, Gustavo, Ittmann, Michael M., Weigel, Nancy L., Agoulnik, Irina U.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077543/
https://ncbi.nlm.nih.gov/pubmed/21224358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2314
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