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Modeling General Proteostasis: Proteome Balance in Health and Disease
Protein function is generated and maintained by the proteostasis network (PN) (Balch et al. (2008) Science, 319:916). The PN is a modular, yet integrated system unique to each cell type that is sensitive to signaling pathways that direct development and aging, and respond to folding stress. Mismanag...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077458/ https://ncbi.nlm.nih.gov/pubmed/21131189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2010.11.001 |
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