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Modeling General Proteostasis: Proteome Balance in Health and Disease

Protein function is generated and maintained by the proteostasis network (PN) (Balch et al. (2008) Science, 319:916). The PN is a modular, yet integrated system unique to each cell type that is sensitive to signaling pathways that direct development and aging, and respond to folding stress. Mismanag...

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Hlavní autoři: Roth, Daniela M., Balch, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077458/
https://ncbi.nlm.nih.gov/pubmed/21131189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2010.11.001
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