Response of Estrogen Receptor-Positive Breast Cancer Tumorspheres to Antiestrogen Treatments

Estrogen signaling plays a critical role in the pathogenesis of breast cancer. Because the majority of breast carcinomas express the estrogen receptor ERα, endocrine therapy that impedes estrogen-ER signaling reduces breast cancer mortality and has become a mainstay of breast cancer treatment. Howev...

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Main Authors: Ao, Ada, Morrison, Brian J., Wang, Heiman, López, J. Alejandro, Reynolds, Brent A., Lu, Jianrong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077404/
https://ncbi.nlm.nih.gov/pubmed/21533195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018810
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