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Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors

The development of intratumoral hypoxia is a universal hallmark of rapidly growing solid tumors. Adaptation to the hypoxic environment, which is critical for tumor cell survival and growth, is mediated primarily through a hypoxia-inducible factor (HIF)-dependent transcriptional program. HIF activate...

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Detalhes bibliográficos
Main Authors: Ao, Ada, Wang, Heiman, Kamarajugadda, Sushama, Lu, Jianrong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409389/
https://ncbi.nlm.nih.gov/pubmed/18509053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711677105
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