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Estrogen-mediated Regulation of Igf1 Transcription and Uterine Growth Involves Direct Binding of Estrogen Receptor α to Estrogen-responsive Elements

Estrogen enables uterine proliferation, which depends on synthesis of the IGF1 growth factor. This proliferation and IGF1 synthesis requires the estrogen receptor (ER), which binds directly to target DNA sequences (estrogen-responsive elements or EREs), or interacts with other transcription factors,...

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Detalhes bibliográficos
Main Authors: Hewitt, Sylvia C., Li, Yin, Li, Leping, Korach, Kenneth S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807324/
https://ncbi.nlm.nih.gov/pubmed/19920132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043471
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