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Estrogen receptor α (ERα)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice

Estrogen receptor α (ERα) modulates gene expression by interacting with chromatin regions that are frequently distal from the promoters of estrogen-regulated genes. Active chromatin-enriched “super-enhancer” (SE) regions, mainly observed in in vitro culture systems, often control production of key c...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Hewitt, Sylvia C., Grimm, Sara A., Wu, San-Pin, DeMayo, Francesco J., Korach, Kenneth S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307205/
https://ncbi.nlm.nih.gov/pubmed/32354741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013666
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