Dysregulation of hypothalamic-pituitary estrogen receptor α–mediated signaling causes episodic LH secretion and cystic ovary

Polycystic ovary syndrome (PCOS) is a hypothalamic-pituitary-gonadal (HPG) axis disorder. PCOS symptoms most likely result from a disturbance in the complex feedback regulation system of the HPG axis, which involves gonadotrophic hormones and ovarian steroid hormones. However, the nature of this com...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Arao, Yukitomo, Hamilton, Katherine J., Wu, San-Pin, Tsai, Ming-Jer, DeMayo, Francesco J., Korach, Kenneth S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2019
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529333/
https://ncbi.nlm.nih.gov/pubmed/30866655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802653RR
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