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aCGH.Spline—an R package for aCGH dye bias normalization

Motivation: The careful normalization of array-based comparative genomic hybridization (aCGH) data is of critical importance for the accurate detection of copy number changes. The difference in labelling affinity between the two fluorophores used in aCGH—usually Cy5 and Cy3—can be observed as a bias...

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Dades bibliogràfiques
Autors principals: Fitzgerald, Tomas W., Larcombe, Lee D., Le Scouarnec, Solena, Clayton, Stephen, Rajan, Diana, Carter, Nigel P., Redon, Richard
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077069/
https://ncbi.nlm.nih.gov/pubmed/21357574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr107
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