aCGH.Spline—an R package for aCGH dye bias normalization

Motivation: The careful normalization of array-based comparative genomic hybridization (aCGH) data is of critical importance for the accurate detection of copy number changes. The difference in labelling affinity between the two fluorophores used in aCGH—usually Cy5 and Cy3—can be observed as a bias...

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Bibliografiske detaljer
Main Authors: Fitzgerald, Tomas W., Larcombe, Lee D., Le Scouarnec, Solena, Clayton, Stephen, Rajan, Diana, Carter, Nigel P., Redon, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077069/
https://ncbi.nlm.nih.gov/pubmed/21357574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr107
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