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aCGH.Spline—an R package for aCGH dye bias normalization

Motivation: The careful normalization of array-based comparative genomic hybridization (aCGH) data is of critical importance for the accurate detection of copy number changes. The difference in labelling affinity between the two fluorophores used in aCGH—usually Cy5 and Cy3—can be observed as a bias...

詳細記述

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書誌詳細
主要な著者: Fitzgerald, Tomas W., Larcombe, Lee D., Le Scouarnec, Solena, Clayton, Stephen, Rajan, Diana, Carter, Nigel P., Redon, Richard
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077069/
https://ncbi.nlm.nih.gov/pubmed/21357574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr107
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