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aCGH.Spline—an R package for aCGH dye bias normalization
Motivation: The careful normalization of array-based comparative genomic hybridization (aCGH) data is of critical importance for the accurate detection of copy number changes. The difference in labelling affinity between the two fluorophores used in aCGH—usually Cy5 and Cy3—can be observed as a bias...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077069/ https://ncbi.nlm.nih.gov/pubmed/21357574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr107 |
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