Synthesis of Biodegradable Multiblock Copolymers by Click Coupling of RAFT-Generated HeterotelechelicPolyHPMA Conjugates

A new strategy for the synthesis of biodegradable high molecular weight N-(2-hydroxypropyl)methacrylamide (HPMA)-based polymeric carriers has been designed. An enzyme-sensitive, alkyne-functionalized, chain transfer agent (CTA-GFLG-alkyne; N(α)-(4-pentynoyl)-N(δ)-(4-cyano-4-(phenylcarbonothioylthio)...

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Main Authors: Yang, Jiyuan, Luo, Kui, Pan, Huaizhong, Kopečková, Pavla, Kopeček, Jindřich
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076950/
https://ncbi.nlm.nih.gov/pubmed/21499527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reactfunctpolym.2010.10.005
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