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Increased phosphorylation of the neuronal L-type Ca(2+) channel Ca(v)1.2 during aging

An increase in Ca(2+) influx through L-type Ca(2+) channels is thought to contribute to neuronal dysfunctions that underlie senile symptoms and Alzheimer's disease. The molecular basis of the age-dependent up-regulation in neuronal L-type Ca(2+) channel activity is largely unknown. We show that...

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Hlavní autoři: Davare, Monika A., Hell, Johannes W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC307685/
https://ncbi.nlm.nih.gov/pubmed/14665691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2236970100
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