CYP2D6 and CYP2C19 in Papua New Guinea: High frequency of previously uncharacterized CYP2D6 alleles and heterozygote excess

Purpose: A high frequency of previously unknown CYP2D6 alleles have been reported in Oceania populations. Genetic and functional properties of these alleles remain unknown. Methods: We performed analyses of the genetic variability of CYP2D6 and CYP2C19 genes using AmpliChip genotyping in cohorts fro...

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Bibliographic Details
Main Authors: von Ahsen, Nicolas, Tzvetkov, Mladen, Karunajeewa, Harin A, Gomorrai, Servina, Ura, Alice, Brockmöller, Jürgen, Davis, Timothy M E, Mueller, Ivo, Ilett, Kenneth F, Oellerich, Michael
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076784/
https://ncbi.nlm.nih.gov/pubmed/21532842
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