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IL-27 and IL-21 are Associated with T Cell IL-10 Responses in Human Visceral Leishmaniasis
IL-10 is believed to underlie many of the immunologic defects in human visceral leishmaniasis (VL). We have identified CD4(+)CD25(−)Foxp3(−)T cells as the major source of IL-10 in the VL spleen. IL-27, a member of the IL-6/IL-12 cytokine family, has been shown to promote development of IL-10 produci...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076633/ https://ncbi.nlm.nih.gov/pubmed/21357266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003588 |
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