Leishmania Specific CD4 T Cells Release IFNγ That Limits Parasite Replication in Patients with Visceral Leishmaniasis

Visceral leishmaniasis (VL) is associated with increased circulating levels of multiple pro-inflammatory cytokines and chemokines, including IL-12, IFNγ, and TNFα, and elevated expression of IFNγ mRNA in lesional tissue such as the spleen and bone marrow. However, an immunological feature of VL pati...

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Detalhes bibliográficos
Main Authors: Kumar, Rajiv, Singh, Neetu, Gautam, Shalini, Singh, Om Prakash, Gidwani, Kamlesh, Rai, Madhukar, Sacks, David, Sundar, Shyam, Nylén, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183461/
https://ncbi.nlm.nih.gov/pubmed/25275531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003198
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