Anti–Interleukin-10 Unleashes Transcriptional Response to Leishmanial Antigens in Visceral Leishmaniasis Patients

Visceral leishmaniasis (VL; Leishmania donovani) cases produce interferon-γ and tumor necrosis factor in response to soluble leishmanial antigen (SLA) in whole-blood assays. Using transcriptional profiling, we demonstrate the impact of interleukin-10 (IL-10), a cytokine implicated in VL, on this res...

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Spremljeno u:
Bibliografski detalji
Izdano u:J Infect Dis
Glavni autori: Singh, Om Prakash, Syn, Genevieve, Nylén, Susanne, Engwerda, Christian, Sacks, David, Wilson, Mary E, Kumar, Rajiv, Chakravarty, Jaya, Sundar, Shyam, Blackwell, Jenefer M, Fakiola, Michaela
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Major Articles and Brief Reports
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881328/
https://ncbi.nlm.nih.gov/pubmed/32614452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa381
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