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Enhanced expression of Toll Like Receptors (TLRs) 2& 4, but not 9, in spleen tissue from visceral leishmaniasis patients

Toll like receptor (TLR) signaling is involved in first line defense against Leishmania parasites by triggering NF-κB activation and down-stream production of pro-inflammatory cytokines. Experimental models of visceral leishmaniasis (VL) support a protective role for TLRs 2, 4 and 9 in host immune r...

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Detalhes bibliográficos
Publicado no:Parasite Immunol
Main Authors: Kumar, Rajiv, Singh, Om Prakash, Gautam, Shalini, Nylen, Susanne, Sundar, Shyam
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246031/
https://ncbi.nlm.nih.gov/pubmed/25244363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pim.12145
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