Epstein–Barr virus latent membrane protein 1 activation of NF-κB through IRAK1 and TRAF6

Epstein–Barr virus latent membrane protein 1 (LMP1) activation of NF-κB is critical for Epstein–Barr virus-infected B lymphocyte survival. LMP1 activates the IκB kinase complex and NF-κB through two cytoplasmic signaling domains that engage tumor necrosis factor receptor-associated factor (TRAF)1/2/...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Luftig, Micah, Prinarakis, Efthimios, Yasui, Teruhito, Tsichritzis, Theodore, Cahir-McFarland, Ellen, Inoue, Jun-Ichiro, Nakano, Hiroyasu, Mak, Tak Wah, Yeh, Wen-Chen, Li, Xiaoxia, Akira, Shizuo, Suzuki, Nobutaka, Suzuki, Shinobu, Mosialos, George, Kieff, Elliott
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307613/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673102/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2136756100
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