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Stereocontrolled Total Syntheses of Isodomoic Acids G and H via a Unified Strategy

Marine neuroexcitatory compounds isodomoic acids G and H were efficiently synthesized from a common intermediate using a silicon-based cross-coupling reaction. Dividing each target compound into the core fragment and the side-chain fragment enabled the synthesis to be convergent. The trans-2,3-disub...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Denmark, Scott E., Liu, Jack H.-C., Muhuhi, Joseck M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076050/
https://ncbi.nlm.nih.gov/pubmed/21121685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo101790z
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