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Total Syntheses of Isodomoic Acids G and H: An Exercise in Tetrasubstituted Alkene Synthesis

A unified approach to the pyrrolidine triacid natural products isodomoic acids G and H has been developed. Total syntheses of both natural products were completed, and determination of the correct stereostructure of isodomoic acid G was established by comparing 5’(R) and 5’(S) isomers to a sample of...

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Bibliographic Details
Main Authors: Ni, Yike, Kassab, Refaie M., Chevliakov, Maxim V., Montgomery, John
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788205/
https://ncbi.nlm.nih.gov/pubmed/19899794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja907931u
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