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Development of a General, Sequential, Ring Closing Metathesis/Intramolecular Cross-Coupling Reaction for the Synthesis of Polyunsaturated Macrolactones

A general strategy for the construction of macrocyclic lactones containing conjugated Z,Z-1,3-diene subunits has been is described. The centerpiece of the strategy is a sequential ring-closing metathesis that forms an unsaturated siloxane ring followed by an intramolecular cross-coupling reaction wi...

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Detalhes bibliográficos
Main Authors: Denmark, Scott E., Muhuhi, Joseck M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923678/
https://ncbi.nlm.nih.gov/pubmed/20666473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1047363
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