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Low Catalyst Loadings in Olefin Metathesis: Synthesis of Nitrogen Heterocycles by Ring Closing Metathesis

(eq 1). [Image: see text] A series of ruthenium catalysts have been screened under ring closing metathesis (RCM) conditions to produce five-, six-, and seven-membered carbamate-protected cyclic amines. Many of these catalysts demonstrated excellent RCM activity and yields with as low as 500 ppm cata...

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Detalhes bibliográficos
Main Authors: Kuhn, Kevin M., Champagne, Timothy M., Hong, Soon Hyeok, Wei, Wen-Hao, Nickel, Andrew, Lee, Choon Woo, Virgil, Scott C., Grubbs, Robert H., Pederson, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871858/
https://ncbi.nlm.nih.gov/pubmed/20141172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol9029808
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