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Role of the β-Subunit Arginine/Lysine Finger in Integrin Heterodimer Formation and Function
Formation of the integrin αβ heterodimer is essential for cell surface expression and function. At the core of the αβ interface is a conserved Arg/Lys “finger” from the β-subunit that inserts into a cup-like “cage” formed of two layers of aromatic residues in the α-subunit. We evaluated the role of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075857/ https://ncbi.nlm.nih.gov/pubmed/18209068 |
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