Vacuole Size Control: Regulation of PtdIns(3,5)P(2) Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P(2)-specific Phosphatase

In the budding yeast Saccharomyces cerevisiae, phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P(2)) is synthesized by a single phosphatidylinositol 3-phosphate 5-kinase, Fab1. Cells deficient in PtdIns(3,5)P(2) synthesis exhibit a grossly enlarged vacuole morphology, whereas increased levels of P...

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Bibliografiske detaljer

Udgivet i:	Mol Biol Cell
Principais autores:	Rudge, Simon A., Anderson, Deborah M., Emr, Scott D.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Cell Biology 2004
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14528018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-05-0297
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